旧版入口 | English

师资队伍
杰出人才
博士后

您当前所在位置: 首页 - 师资队伍 - 药物分析学系 - 正文

吴曈勃

来源: 发布时间 2018-10-25 16:04:36 点击数:

吴曈勃

 

吴曈勃,男,博士,副教授,博士生导师。本硕博均就读于北京大学,师从化学与分子工程学院赵美萍教授,获得理学博士学位,并被评为北京市优秀毕业生、北京大学优秀毕业生。后赴加拿大阿尔伯塔大学医学院病理与实验医学系开展博士后研究,导师乐晓春(X. Chris Le)院士。主要研究兴趣为疾病相关生物标志物的检测及其在精准医疗、药效评价等方面的应用。

联系方式:wutongbo@hust.edu.cn

教育背景

2012. 9-2017. 7 理学博士 北京大学 化学与分子工程学院

2008. 9-2012. 7 理学学士 北京大学 化学与分子工程学院

2009. 9-2012. 7 经济学学士(双学位) 北京大学 国家发展研究院

工作经历

2017. 8-2018. 10 博士后 加拿大阿尔伯塔大学 病理与实验医学系

2018.10至今 副教授,华中科技大学 同济医学院药学院

代表论文

1. Tongbo Wu, Yufei Yang, Wei Chen, Jiayu Wang, Ziyu Yang, Shenlin Wang, Xianjin Xiao, Mengyuan Li and Meiping Zhao*, Noncanonical substrate preference of lambda exonuclease for 5-nonphosphate-ended dsDNA and a mismatch-induced acceleration effect on the enzymatic reaction, Nucleic Acids Research, 2018, 46, 3119-3129. (IF=11.561)

2. Tongbo Wu, Wei Chen, Ziyu Yang, Haocheng Tan, Jiayu Wang, Xianjin Xiao, Mengyuan Li and Meiping Zhao*, DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA, Nucleic Acids Research, 2018, 46, e24. (IF=11.561)

3. Tongbo Wu, Xianjin Xiao, Zhe Zhang and Meiping Zhao*, Enzyme-mediated single-nucleotide variation detection at room temperature with high discrimination factor, Chemical Science, 2015, 6, 1206–1211. (IF=9.063)

4. Tongbo Wu, Xianjin Xiao, Feidan Gu and Meiping Zhao*, Sensitive discrimination of stable mismatched base pairs by abasic site modified fluorescent probe and lambda exonuclease, Chemical Communications, 2015, 51, 17402–17405.  (IF=6.290)

5. Xuzhe Zhang†, Tongbo Wu†, Hongbo Wang, Yufan Zou, Wei Chen, Meiping Zhao, Shanshan Wang* and Xianjin Xiao*, A time-dependent fluorescent biosensor for uracil-DNA glycosylase detection based on the uracil inhibition effect towards archaebacterial DNA polymerases, Sensors and Actuators B: Chemical, 2018, 270, 277-282. (IF=5.667)

6. Tongbo Wu, Yuan Liang, Xiaocui Zhu, Meiping Zhao* and Huwei Liu, Separation and quantification of four isomers of indole-3-acetyl-myo-inositol in plant tissues using high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry, Analytical and Bioanalytical Chemistry, 2014, 406, 3239–3247. (IF=3.307)

 

华中科技大学同济医学院办公室 鄂ICO备030193 地址:湖北省武汉市汉口航空路13号 邮政编码:430030