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师资队伍
杰出人才
博士后

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辜良虎

来源: 发布时间 2018-11-10 13:51:24 点击数:

辜良虎

辜良虎,男,博士,副教授,博士生导师。本硕均就读于华中科技大学,师从化学与化工学院龚跃法教授,获得理学本科和硕士学位,并被评为华中科技大学优秀毕业生。后赴德国马普煤炭研究所攻读博士学位,导师Alois Fürstner教授和Manuel Alcarazo教授。博士毕业后进入药明康德新药开发有限公司国内新药服务部从事新药开发服务。2018年11月加入同济药学院,主要研究兴趣为有机合成方法学和对具有抗菌和抗肿瘤活性天然产物的仿生合成。

联系方式:gulianghu@hust.edu.cn

教育经历

09/2012 – 06/2016自然科学博士 德国多特蒙德工业大学(马普煤炭研究所)

09/2009 – 03/2012理学硕士 华中科技大学 化学与化工学院

09/2005 – 06/2009理学本科 华中科技大学 化学与化工学院

工作经历

11/2018-至今 副教授,华中科技大学同济医学院药学院

09/2016-10/2018 高级研究员 药明康德新药开发有限公司 国内新药服务部

代表论文

1 L. Gu, Y. Zheng, E. Haldón, R. Goddard, E. Bill, W. Thiel, M. Alcarazo,α-Radical Phosphines: Synthesis, Structure and ReactivityAngew. Chem. Int. Ed.2017,56, 8790.(IF: 11.9)

2 L.Gu, L.M. Wolf, A.Zieliński, W.Thiel, M.Alcarazo,αDicationic Chelating Phosphines: Synthesis and Application to the Hydroarylation of DienesJ. Am. Chem. Soc.2017,139, 4948.(IF: 13.8)

3 L. Gu,L. M. Wolf, W. Thiel, C. W. Lehmann, M. AlcarazoReductive Elimination of C6F5-C6F5from Pd(II) Complexes: Influence of αDicationic Chelating PhosphinesOrganometallics,2018,37, 665.(IF: 3.8)

4 L. Gu, G. Gopakumar, P. Gualco, W. Thiel and M. AlcarazoBis- and Tris(pyrazolyl)borate/Methane-Stabilized PIII-Centered CationsChem. Eur. J.2014,20, 8575-8578.(IF: 5.3)

5 L. Gu, Y. Zhou, J. Zhang, Y. Gong* A highly chemo- and enantioselective nitroaldol reaction of haloenals: preparation of chiral functionalized allylic alcoholsTetrahedron: Asymmetry2012,23, 124–129.(IF: 2.1)

6 J. Carreras, G. Gopakumar,L. Gu, A. Gimeno, J. Petuškova, W. Thiel, and M. Alcarazo Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π-Acidic CatalystsJ. Am. Chem. Soc. 2013,135, 18815.(IF: 13.8)

7 E. H. Haldon, A. Kozma, H. Tinnermann,L. Gu, R. Goddard, M. Alcarazo*Synthesis and Reactivity of α-Cationic Phosphines: The Effect of Imidazolinium and Amidinium SubstituentsDalton Trans., 2016,45, 1872-1876(IF: 4.0)

8 J. Zhang, L. Liu, J. Duan,L. Gu, B. Chen T. Sun Y. Gong Stereoselective One‐Pot Sequential Dehydrochlorination/trans‐Hydrofluorination Reaction ofβ‐Chloro‐α,β‐unsaturated Aldehydes or Ketones: Facile Access to (Z)‐β‐Fluoro‐β‐arylenals/β‐Fluoro‐β‐arylenonesAdv. Synth. Catal. 2017,359, 4348.(IF: 5.6)

9 M. Wei, Y. Zhou,L. Gu, F. Luo*, F. Zhang*Asymmetric organocatalytic Michael-Hemiacetalization reaction: access to chiral spirocis-δ-lactones by in situ oxidation of spiroδ-lactols.Tetrahedron Lett.,2013, 54,2546-2548.(IF: 2.2)

10 J. Zhang,L. Gu, Y. Gong*Direct Vinylogous Aldol Reaction Triggered by Tetrabutylammonium Fluoride: A Highly Regioselective and Diastereoselective Addition of Cyclic β-Haloenals to Aromatic AldehydesSynlett2012, 23,468–472.(IF: 2.1)

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