旧版入口 | English

师资队伍
杰出人才
博士后

您当前所在位置: 首页 - 师资队伍 - 生物药学系 - 正文

陈红

来源: 发布时间 2018-05-10 10:43:02 点击数:

研究方向:1. 糖尿病及代谢综合征;

      2. 急性肾损伤;

      3. 多肽药物在肾脏疾病中治疗。

联系方式:chsummersky@163.com

 

工作与教育经历:

2017/07-至今,华中科技大学,药学院生物药学系,讲师

2014/07-2017/07,华中科技大学,公共卫生学院流行病与卫生统计学系,

2009/09-2014/06,华中科技大学,药学院生物药学系,博士

2004/09-2009/06,沈阳药科大学,药学院药学系,学士


主持科研项目:

1.    国家自然科学基金青年项目, 31500941,脂肪因子Apelin对急性肾损伤的保护机制研究

2.    华中科技大学自主创新基金面上项目,ELA多肽在急性肾损伤中的作用研究

3.    中国博士后科学基金第九批特别资助项目,2016T90692H3K27甲基化在糖尿病肾病中的作用机制研究

4.    中国博士后科学基金面上项目,2015M572149Apelin对缺血再灌注型急性肾损伤的保护机制研究

 

代表性研究成果

(1) Chen Hong, Wang Lin, Wang Wenjun, Cheng Cheng, Zhang Yu, Zhou Yu, Wang Congyi, Miao Xiaoping, Wang Jiao, Wang Chao, Li Jianshuang, Zheng Ling, Huang Kun*, ELABELA and an ELABELA fragment protect against AKI. J Am Soc Nephrol, 2017 Sep; 28(9):2694-2707

(2) Chen Hong, Wan Danyang, Wang Lin, Peng Anlin, Xiao Hongdou, Petersen R.Bobert, Liu Chengyu, Zheng Ling*, Huang Kun*, Apelin protects against acute renal injury by inhibiting TGF-b1, BBA - Molecular Basis of Disease, 2015 Jul; 1852(7):1278-87  

(3) Chen Hong, Li Jianshuang, Jiao Lihua, Petersen R.Bobert, Li Jiong, Peng Anlin, Zheng Ling*, Huang Kun*, Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse, The Journal of Physiology, 2014, 592, 505-521

(4) Chen Hong, Liu Chengyu, Cheng Cheng, Zheng Ling, Huang Kun*, Effects of apelin peptides on diabetic complications, Curr Protein Pept Sci, 2018, 19(2):179-189

(5) Chen Hong #, Zheng Chenghong #, Zhang Xin, Li Jianshuang, Li Jiong, Zheng Ling*, Huang Kun*, Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice, Peptides, 2011, 32, 1634-1639

(6) Wang Leilei, Chen Hong, Huang Kun*, Zheng Ling*, Elevated Histone Acetylations in Muller Cell Contribute to Inflammation: A Novel Inhibitory Effect of Minocycline, Glia, 2012, 60, 1896-1905

(7) Huang Jin#, Wan Danyang#, Li Jianshuang, Chen Hong, Huang Kun, Zheng Ling*, Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury, Epigenetics, 2015, 10, 1-11

(8) Li Jiong, Huang Jin, Li Jianshuang, Chen Hong, Huang Kun*, Zheng Ling*, Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets, Journal of Hepatology, 2012, 56, 900-907.

(9) Wang Wenjun, Wang Qing, Wan Danyang, Sun Yue, Wang Lin, Chen Hong, Liu Chengyu, Petersen R.Bobert, Li Jianshuang, Xue Weili, Zheng Ling*, Huang Kun*, Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy, Autophagy, 2017 May 4;13(5):941-954

(10) Ding Yinwen#, Li Jiong#, Liu Shanshan, Zhang Le, Xiao Hongdou, Li Jianshuang, Chen Hong, Petersen R.Bobert, Huang Kun*, Zheng Ling*, DNA hypomethylation of inflammation associated genes in adipose tissue of female mice after multigenerational high fat diet feeding, International Journal of Obesity, 2014, 38, 198-204


华中科技大学同济医学院办公室 鄂ICO备030193 地址:湖北省武汉市汉口航空路13号 邮政编码:430030