姓名：邓斌出生年月：1990.6
电话：18164108181邮箱：dengbin@hust.edu.cn
工作经历
2016-今华中科技大学同济医学院附属协和医院副主任药师
2023.12-至今澳大利亚昆士兰大学访问学者
教育经历
2013-2016澳大利亚昆士兰大学联合培养（博士）导师：Robert Gilbert（中组织部外专千人计划入选专家，澳大利亚皇家科学院院士、化学院院士）
2012-2016华中科技大学同济医学院药学院药物分析学硕博连读导师：
Robert Gilbert、陈家春
2008-2012重庆医科大学中药学本科
研究方向
生物大分子结构与功能相关性，内分泌药物药理
承担或参与课题
1.湖北省自然科学基金面上项目，2022CFB092，PPP1R3G动态性调控GS失调在肝糖原分子结构节律性变化紊乱中的作用及小檗碱干预研究，2022.06-2024.09, 8万，主持
2.吴阶平基金会科研项目，阿哌沙班用于骨科大手术相关静脉血栓预防的临床综合评价研究，2023.06-2025.06, 5万，主持
3.国家自然科学基金青年项目，81803799，小檗碱通过负向调控GS修复受损
肝糖原分子结构的作用及机制研究，2019/01-2021/12，23万，主持
4.国家自然科学基金青年项目，81703630，他克莫司通过抑制Reg3表达机器介
导的β细胞再生致移植术后新发糖尿病的作用及机制研究，2018/01-2020/12,20
万，参加
5.华中科技大学自主创新基金面上项目，2017KFYXJJ252，二甲双胍修复受损肝糖原分子结构作用研究，2017/01-2019/12，主持
学术兼职
中国人体健康科技促进会临床微生物与感染精准检测专委会委员
湖北省医院协会药事专委会青年学组副主任组员
武汉药学会药事管理专委会常务委员兼秘书
《临床药物治疗杂志》青年编委
《药物评价研究杂志》青年编委
《医药导报》青年编委
Carbohydrate polymers, International journal of biological micromodules, Journal of Ethnopharmacology等期刊审稿人
发表论文
1. Chen C, Liu XC,Deng B. Protective Effects of Berberine on Nonalcoholic Fatty Liver Disease in db/db Mice via AMPK/SIRT1 Pathway Activation. Curr Med Sci. 2024 Jul 23. doi: 10.1007/s11596-024-2914-y. Epub ahead of print. PMID: 39039374.
2. Wang Z, Min X, Hu Z, Sullivan MA, Tang Y, Wang L, Gilbert RG, Shi C,Deng B. The fragility of liver glycogen from humans with type 2 diabetes: A pilot study. Int J Biol Macromol. 2022 Nov 30;221:83-90. doi: 10.1016/j.ijbiomac.2022.08.212. Epub 2022 Sep 6. PMID: 36075306
3. Zhang QL, Liu XC, Sullivan MA, Shi C,Deng B. Protective Effect of Yi Shen Pai Du Formula Against Diabetic Kidney Injury via Inhibition of Oxidative Stress, Inflammation and Epithelial to Mesenchymal Transition in db/db Mice. Oxidative Medicine and Cellular Longevity 2021.
4. Shi C, Tingting W, Li JP, Sullivan MA, Wang C, Wang H,Deng B, Zhang Y. Comprehensive Landscape of Heparin Therapy for COVID-19. Carbohydr Polym.2021 Feb 15;254:117232.
5. Liu X, Wang K, Zhou J, Sullivan MA, Liu Y, Gilbert RG,Deng B. Metforminand Berberine suppress glycogenolysis by inhibiting glycogen phosphorylase and stabilizing the molecular structure of glycogen in db/db mice. Carbohydr Polym. 2020 Sep 1;243:116435.
6. Liu Y, Yang L, Zhang Y, Liu X, Wu Z, Gilbert RG,Deng B, Wang K. Dendrobium officinale polysaccharide ameliorates diabetic hepatic glucose metabolism via glucagon-mediated signaling pathways and modifying liver-glycogen structure. J Ethnopharmacol. 2020 Feb 10;248:112308.
7. Z Hu,B Deng, X Tan, H Gan, C Li, SS Nada, MA Sullivan, J Li, X Jiang, ELi, RG Gilbert. Diurnal changes of glycogen molecular structure in healthy and diabetic mice. Carbohydrate Polymers 185 124-52 (2018).
8.Deng, Bin, Sullivan, Mitchell A, Wu, Alex Chi, Li, Jialun, Chen, Cheng, Gilbert, Robert G*. The mechanism for stopping chain and total-molecule growth in complex branched polymers, exemplified by glycogen. Biomacromolecules, 2015, 16 (6): 1870-2.
9.Deng, Bin, Sullivan, Mitchell A., Li, Jialun, Tan, Xinle, Zhu, Chengjun, Schulz, Benjamin L., Gilbert, Robert G*. Molecular structure of glycogen in diabetic liver. Glycoconjugate Journal, 2015, 32 (3-4): 113-8.
10.Deng, Bin, Sullivan, Mitchell A.#,Chen, Cheng,Li, Jialun,Powell, Prudence O.,Hu, Zhenxia,Gilbert, Robert G*. Molecular Structure of Human-Liver Glycogen. PLoS One, 2016, 11 (3): e0150540.
11. Hu, Zhenxia, Tan, Xinle, Deng, Bin, Gan, Hua, Jiang, Xiaoyin, Wang, Kai, Li, Cheng, Li, Enpeng and Gilbert, Robert G. Implications for biological function of lobe dependence of the molecular structure of liver glycogen. European Polymer Journal, 90 105-113 2017. doi:10.1016/j.eurpolymj.2017.03.009
12. Sullivan, Mitchell A, Li, Shihan, Aroney, Samuel TN, Deng, Bin, Li, Cheng, Roura, Eugeni, Schulz, Benjamin L, Harcourt, Brooke E, Forbes, Josephine M, Gilbert, Robert G.*. A rapid extraction method for glycogen from formalin-fixed liver. Carbohydrate Polymers 118 (1), 9-15, 2015
13. Jiang, Xiaoyin, Zhang, Peng, Li, Shihan, Tan, Xinle, Hu, Zhenxia, Deng, Bin, Wang, Kai, Li, Cheng, Sullivan, Mitchell A., Li, Enpeng, Gilbert, Robert. G*.Molecular-size dependence of glycogen enzymatic degradation and its importance for diabetes. European Polymer Journal 82, 175-180, 2016.
14. Xiao, Zuo Qi, Wang, Yong Long, Yue, Yao Dong, Zhang, Yu Tang, Chen, Cui Ping, Wan, Luo Sheng, Deng, Bin, Liu, Zhao Xia, Chen, Jia Chun.* Preventive effects of polysaccharides from Liriope spicata var. prolifera on diabetic nephropathy in rats. International Journal of Biological Macromolecules 61 (10), 114-120, 2013.
