德曲妥珠单抗治疗HER2阳性乳腺癌的临床综合评价—— 其他纵向项目，主持
口服香菇多糖免疫调节的PK/PD研究：派氏结摄取动力学与T细胞双轴协同激活机制—— 其他纵向项目，主持
香菇活性多糖口服药代动力学特征及机制研究—— 省级项目，主持
香菇多糖靶标CD133+癌细胞负调控CD133/SCGB2A2信号轴发挥抗乳腺癌作用发挥的机制研究—— 其他纵向项目，主持
香菇多糖负调控CD133蛋白激活自噬性死亡及凋亡协同发挥直接抗结肠癌作用的机制研究—— 其他纵向项目，主持
香菇多糖靶标CD133+癌细胞发挥"特异性"直接抗结肠癌作用的机制研究—— 国家基金委青年项目，主持
代表性成果
Angelica sinensis polysaccharides modulate iron metabolism and macrophage polarization to alleviate rheumatoid arthritis.International Journal of Biological Macromolecules, 2026
Sulfated modification and biomedical applications of β-glucans: A review.Carbohydrate Polymer Technologies and Applications, 2026
Mechanistic insights into the hepatic metabolism of lentinan: A TLR2-ROS-lysosome axis.International Journal of Biological Macromolecules, 2026
Mucormycosis in Paediatric Patients After Haematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.Mycoses, 2025
Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis.Frontiers in Pharmacology, 2025
A novel method to quantify Dendrobium officinale polysaccharides in biological samples via 99mTc-labelling and radioHPGPC analysis.Carbohydrate Polymers, 2025
Astragalus polysaccharides alleviate DSS-induced ulcerative colitis in mice by restoring SCFA production and regulating Th17/Treg cell homeostasis in a microbiota-dependent manner.Carbohydrate Polymers, 2025
Angelica sinensis polysaccharide could alleviate the gastrointestinal damage in alcoholic fatty liver disease mice: Regulation of alcohol metabolism and enhancement of short-chain fatty acids utilization.Journal of Ethnopharmacology, 2025
Insights into oral lentinan immunomodulation: Dectin-1-mediated lymphatic transport from Peyer's patch M cells to mononuclear phagocytes.Carbohydrate Polymers, 2024
Intestinal lymphatic transport ofSmilax chinaL. pectic polysaccharide via Peyer's patches and its uptake and transport mechanisms in mononuclear phagocytes.Carbohydrate Polymers, 2024
Protective effect of Angelica sinensis polysaccharide on pregnant rats suffering from iron deficiency anemia via regulation of the hepcidin-FPN1 axis.International Journal of Biological Macromolecules, 2024
Formyl peptide receptor 2 is a potential biomarker and therapeutic target for inflammatory bowel disease.Acta Pharmacologica Sinica, 2023
Initial sirolimus dosage recommendations for pediatric patients with PIK3CD mutation-related immunodeficiency disease.Frontiers in Pharmacology, 2022
Lentinan inhibited colon cancer growth by inducing endoplasmic reticulum stress-mediated autophagic cell death and apoptosis.Carbohydrate Polymers, 2021
Spontaneous oxidative cyclisations of 1,3-dihydroxy-4-dimethylallylnaphthalene to tricyclic derivatives.Organic & Biomolecular Chemistry, 2020
